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CD45 Mouse mAb

簡要(yào)描述:CD45 Mouse mAb

  • 產(chǎn)品型號:780015
  • 廠商性(xìng)質(zhì):生產廠家
  • 更(gēng)新時間:2025-08-22
  • 訪  問(wèn)  量:623
產品(pǐn)詳(xiáng)情(qíng)
稀(xī)釋比
FC-1:100
SwissProt ID
P08575
宿主
Mouse
偶聯物
Unconjugated
修飾
Unmodified
基因 ID
5788
基(jī)因名(míng)
PTPRC
亞型
IgG2a
克隆性
Monoclonal Antibody
克隆號(hào)
FC-B3
免(miǎn)疫原(yuán)
A synthesized peptide derived from human CD45
研(yán)究(jiū)領域
Immunology
背(bèi)景信息
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
純化(huà)方式
Affinity Purified
形式(shì)
Liquid
存儲緩(huǎn)衝液
Liquid in 0.01M PBS, pH 7.4, 0.2%(w/v) BSA, 0.09%(w/v) NaN3
保存溫(wēn)度
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.


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