FC-5μL per test for million cells or whole blood in 100 μL volume.
SwissProt ID
P01731
宿主
Rat
偶(ǒu)聯物
PErCP
修飾(shì)
Unmodified
基因 ID
12525
基因名(míng)
Mouse CD8a
亞(yà)型
IgG2a
克(kè)隆性
Monoclonal Antibody
克隆號(hào)
53-6.7
免疫原
A synthesized peptide derived from Mouse CD8a
研(yán)究領(lǐng)域(yù)
Immunology
背景信息
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
純(chún)化(huà)方(fāng)式
Affinity Purified
形式
Liquid
存(cún)儲緩(huǎn)衝液(yè)
Liquid in PBS with 0.05% Proclin300, 1% BSA
保存溫度
Store at 2-8°C..Avoid light.Avoid freeze/thaw cycles.