Rat Anti-Mouse CD8a mAb (AF488)

簡要(yào)描述：應(yīng)用
FC
反應種屬(shǔ)
Mouse

產(chǎn)品型號：781055
廠商(shāng)性質(zhì)：生產廠(chǎng)家
更新(xīn)時間：2025-08-21
訪(fǎng) 問(wèn) 量(liáng)：441

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產品介紹：

產品詳情

同源性(xìng)比對(duì)：

P01731

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稀釋比

FC-5μL per test for million cells or whole blood in 100 μL volume.

SwissProt ID

P01731

宿主

Rat

偶(ǒu)聯(lián)物

AF488. Ex:490nm.Em:525nm.

修(xiū)飾

Unmodified

基因(yīn) ID

12525

基因(yīn)名

Mouse CD8a

亞型(xíng)

IgG2a

克隆(lóng)性

Monoclonal Antibody

克隆號(hào)

53-6.7

免疫原

A synthesized peptide derived from Mouse CD8a

研(yán)究領域

Immunology

背景(jǐng)信息(xī)

CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

純化(huà)方式(shì)

Affinity Purified

形(xíng)式(shì)

Liquid

存儲(chǔ)緩衝(chōng)液(yè)

Liquid in PBS with 0.05% Proclin300, 1% BSA

保存(cún)溫度(dù)

Store at 2-8°C..Avoid light.Avoid freeze/thaw cycles.