Rat Anti-Mouse F4/80 mAb (AF488)

簡(jiǎn)要(yào)描(miáo)述(shù)：Rat Anti-Mouse F4/80 mAb (AF488)

產品型號(hào)：781021
廠(chǎng)商(shāng)性(xìng)質：生產廠家
更(gēng)新(xīn)時(shí)間：2025-08-21
訪(fǎng) 問量：406

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產品(pǐn)介(jiè)紹(shào)：

產(chǎn)品詳情

同(tóng)源(yuán)性比對(duì)：

Q61549

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稀(xī)釋(shì)比

FC-5μL per test for million cells or whole blood in 100 μL volume.

SwissProt ID

Q61549

宿主(zhǔ)

Rat

偶聯物(wù)

AF488. Ex:490nm.Em:525nm.

修飾

Unmodified

基因 ID

13733

基因名

Mouse F4/80

亞型(xíng)

IgG2b

克隆性

Monoclonal Antibody

克隆(lóng)號

CI:A3-1

免(miǎn)疫原

A synthesized peptide derived from Mouse F4/80

研(yán)究領域

Immunology

背景(jǐng)信(xìn)息

F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.

純(chún)化(huà)方式

Affinity Purified

形(xíng)式

Liquid

存儲(chǔ)緩(huǎn)衝(chōng)液(yè)

Liquid in PBS with 0.05% Proclin300, 1% BSA

保存(cún)溫度

Store at 2-8°C..Avoid light.Avoid freeze/thaw cycles.